Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.43 |
| ▸ | NOS3 | P29474 | 5/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 3/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991158 | 0.91 | NOS2 (0.43) | NOS2NOS3CCR1CCR5CCR8 | |
| SCHEMBL6597630 | 0.88 | CES1 (0.36) | NOS2NOS3CCR1CCR5CCR8 | |
| SCHEMBL13168838 | 0.87 | NOS2 (0.42) | NOS2NOS3CCR1CCR5CCR8 | |
| SCHEMBL6407586 | 0.85 | MAPT (0.40) | MEN1KMT2ATHRBTDP1USP8 | |
| SCHEMBL6410245 | 0.85 | ALDH1A1 (0.35) | NOS2NOS3CCR1CCR5CCR8 | |
| SCHEMBL6407115 | 0.85 | TDP2 (0.55) | TDP2NSD2PAX8MEN1KMT2A | |
| Cleistopholine SCHEMBL6358965 | 0.84 | ALDH1A1 (0.55) | TDP2NSD2PAX8MEN1KMT2A | |
| SCHEMBL6415761 | 0.82 | SMN1; SMN2 (0.39) | PAX8MEN1KMT2ATDP1GAA | |
| SCHEMBL6408518 | 0.81 | TDP2 (0.55) | TDP2NSD2PAX8MEN1KMT2A | |
| SCHEMBL28588064 | 0.81 | ADORA2A (0.54) | TDP2NSD2PAX8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080090-B1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIV MADRID COMPLUTENSE (ES) | 2004-02-25 | — | — | EP | claimed |
| US-6525063-B2 | 3,7-dimethyl-1,5-diazaanthraquinone for example | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2003-02-25 | — | — | US | claimed |
| US-20020099066-A1 | Antitumour 1,5-diazaanthraquinones | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2002-07-25 | — | — | US | claimed |
| EP-1080090-B1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIV MADRID COMPLUTENSE (ES) | 2004-02-25 | — | — | EP | disclosed |
| US-6525063-B2 | 3,7-dimethyl-1,5-diazaanthraquinone for example | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2003-02-25 | — | — | US | disclosed |
| US-20020099066-A1 | Antitumour 1,5-diazaanthraquinones | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2002-07-25 | — | — | US | disclosed |
| EP-1080090-A1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999059996-A1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099066-A1 | Antitumour 1,5-diazaanthraquinones | PRMT7, TPD52L2, DRD4 | NOS2 1547/4885NOS3 1510/4885CCR1 2432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.