SCHEMBL7991158

SCHEMBL7991158

Cc1ccnc2c1C(=O)C(=O)c1c(C)ccnc1-2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 6/20 0.43
NOS3 P29474 5/20 0.43
CCR1 P32246 1/20 0.39
CCR5 P51681 1/20 0.39
CCR8 P51685 1/20 0.39
TDP2 O95551 2/20 0.38
NSD2 O96028 2/20 0.38
PAX8 Q06710 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ABL1 P00519 1/20 0.38
PLCG1 P19174 1/20 0.38
CES1 P23141 1/20 0.38
RIN1 Q13671 1/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GAA P10253 1/20 0.38
NQO1 P15559 1/20 0.36
POR P16435 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6597622 0.91 NOS2 (0.43) NOS2NOS3CCR1CCR5CCR8
Onychine SCHEMBL31040561 0.80 ALDH1A1 (0.55) TDP2NSD2PAX8MEN1KMT2A
Cleistopholine SCHEMBL6358965 0.80 ALDH1A1 (0.55) TDP2NSD2PAX8MEN1KMT2A
Onychine SCHEMBL8548579 0.80 ALDH1A1 (0.55) TDP2NSD2PAX8MEN1KMT2A
SCHEMBL6597630 0.80 CES1 (0.36) NOS2NOS3CCR1CCR5CCR8
SCHEMBL13168838 0.78 NOS2 (0.42) NOS2NOS3CCR1CCR5CCR8
SCHEMBL6410245 0.77 ALDH1A1 (0.35) NOS2NOS3CCR1CCR5CCR8
SCHEMBL6407115 0.77 TDP2 (0.55) TDP2NSD2PAX8MEN1KMT2A
SCHEMBL6407586 0.77 MAPT (0.40) MEN1KMT2ATHRBTDP1ALDH1A1
SCHEMBL6408518 0.77 TDP2 (0.55) TDP2NSD2PAX8MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841825-A Late transition metal catalyst for preparing bimodal UHMWPE, ligand thereof, preparation method and application thereof 璞烯晶新材料(上海)有限公司 2025-04-18 CN claimed
CN-119841825-A Late transition metal catalyst for preparing bimodal UHMWPE, ligand thereof, preparation method and application thereof 璞烯晶新材料(上海)有限公司 2025-04-18 CN disclosed
CN-119735721-A High-performance UHMWPE (ultra-high molecular weight polyethylene) slurry method and process 璞烯晶新材料(上海)有限公司 2025-04-01 CN disclosed
US-6288229-B1 BIPYRIDINE COMPLEXES WITH RUTHENIUM COMPLEXES SECRETARY OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2001-09-11 US disclosed