Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23235907 | 0.93 | ALDH1A1 (0.55) | ALDH1A1PABPC1PTPRCCTSLCTSS | |
| Onychine SCHEMBL31040561 | 0.93 | ALDH1A1 (0.55) | ALDH1A1PTPRCCTSLCTSSPTPN13 | |
| Onychine SCHEMBL8548579 | 0.93 | ALDH1A1 (0.55) | ALDH1A1PTPRCCTSLCTSSPTPN13 | |
| SCHEMBL6408518 | 0.86 | TDP2 (0.55) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL6407115 | 0.86 | TDP2 (0.55) | PTPRCCTSLCTSSPTPN13TDP2 | |
| SCHEMBL6597622 | 0.84 | NOS2 (0.43) | ALDH1A1PTPRCCTSLCTSSPTPN13 | |
| SCHEMBL28588064 | 0.82 | ADORA2A (0.54) | ALDH1A1PTPRCNPC1CYP3A4TSHR | |
| SCHEMBL7991158 | 0.80 | NOS2 (0.43) | ALDH1A1PTPRCCTSLCTSSPTPN13 | |
| SCHEMBL7814111 | 0.79 | ALDH1A1 (0.52) | ALDH1A1PABPC1PTPRCCTSLCTSS | |
| SCHEMBL9095693 | 0.76 | ALDH1A1 (0.49) | ALDH1A1PABPC1PTPRCCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680481-B1 | DERIVATES OF AZAANTHRAQUINONE AND AZAXANTHONE, HERBICIDES AND PLANT GROWTH REGULATORS CONTAINING THE SAME | BASF AG (DE) | 1998-04-01 | — | — | EP | claimed |
| EP-0588796-A1 | NEW COMPOUNDS AND COMPOSITIONS USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1994-03-30 | — | — | EP | claimed |
| WO-1992022297-A1 | NEW COMPOUNDS AND COMPOSITIONS USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1992-12-23 | — | — | WO | claimed |
| US-20230330045-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | COLLABORATIONS PHARMACEUTICALS, INC. | 2023-10-19 | — | — | US | disclosed |
| EP-4208257-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | Collaborations Pharmaceuticals, Inc. (US) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022061019-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | COLLABORATIONS PHARMACEUTICALS, INC. (US) | 2022-03-24 | — | — | WO | disclosed |
| CN-101712648-B | Synthesis method of azepine anthraquinone | NANJING UNIVERSITY OF TECHNOLOGY | 2011-11-09 | — | — | CN | disclosed |
| CN-101712648-A | Synthesis method of azepine anthraquinone | NANJING UNIVERSITY OF TECHNOLOGY | 2010-05-26 | — | — | CN | disclosed |
| US-6844353-B2 | Fungicidal properties of sampangine and its analogs to agriculturally important fungal plant pathogens | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2005-01-18 | — | — | US | disclosed |
| WO-2004086861-A2 | FUNGICIDAL PROPERTIES OF SAMPANGINE AND ITS ANALOGS TO AGRICULTURALLY IMPORTANT FUNGAL PLANT PATHOGENS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2004-10-14 | — | — | WO | disclosed |
| US-20040192721-A1 | Fungicidal properties of sampangine and its analogs to agriculturally important fungal plant pathogens | UNIVERSITY OF MISSISSIPPI, THE | 2004-09-30 | — | — | US | disclosed |
| EP-0588796-A1 | NEW COMPOUNDS AND COMPOSITIONS USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1994-03-30 | — | — | EP | disclosed |
| EP-0556319-A4 | — | — | 1994-01-19 | — | — | EP | disclosed |
| EP-0556319-A1 | SAMPANGINE AND DERIVATIVES USEFUL AS ANTIFUNGAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1993-08-25 | — | — | EP | disclosed |
| US-5227383-A | Sampangine analogs | THE UNIVERSITY OF MISSISSIPPI (US) | 1993-07-13 | — | — | US | disclosed |
| US-5227383-A | Sampangine analogs | THE UNIVERSITY OF MISSISSIPPI (US) | 1993-07-13 | — | — | US | disclosed |
| WO-1992022297-A1 | NEW COMPOUNDS AND COMPOSITIONS USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1992-12-23 | — | — | WO | disclosed |
| WO-1992022297-A1 | NEW COMPOUNDS AND COMPOSITIONS USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1992-12-23 | — | — | WO | disclosed |
| US-5128344-A | SAMPANGINE AND DERIVATIVES USEFUL AS AN ANTIFUNGAL AGENT | UNIVERSITY OF MISSISSIPPI (US) | 1992-07-07 | — | — | US | disclosed |
| WO-1992007565-A1 | SAMPANGINE AND DERIVATIVES USEFUL AS ANTIFUNGAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1992-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192721-A1 | Fungicidal properties of sampangine and its analogs to agriculturally important fungal plant pathogens | SAMSN1, SAMHD1, SPIN4 | ALDH1A1 1466/4885PABPC1 809/4885PTPRC 3776/4885 |
| US-20230330045-A1 | THE ANTIVIRAL DRUG TILORONE IS A POTENT AND SELECTIVE INHIBITOR OF ACETYLCHOLINESTERASE | ACHE, BCHE, ACE | ALDH1A1 3807/4885PABPC1 3327/4885PTPRC 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.