Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595449 | 0.91 | ABCB11 (0.55) | ABCB11CCR2 | |
| SCHEMBL6598022 | 0.81 | ABCB11 (1.00) | ABCB11CCR2 | |
| SCHEMBL6595450 | 0.80 | CCR2 (0.50) | ABCB11CCR2 | |
| SCHEMBL4562830 | 0.77 | CCR2 (0.51) | ABCB11CCR2 | |
| SCHEMBL6300727 | 0.77 | CCR2 (1.00) | ABCB11CCR2 | |
| SCHEMBL3298276 | 0.77 | CCR2 (0.51) | ABCB11CCR2 | |
| SCHEMBL6303492 | 0.77 | CCR2 (0.74) | ABCB11CCR2 | |
| SCHEMBL6300905 | 0.76 | CCR2 (1.00) | ABCB11CCR2 | |
| SCHEMBL6300621 | 0.75 | CCR2 (0.81) | ABCB11CCR2 | |
| SCHEMBL7083186 | 0.75 | MAPT (0.43) | ABCB11CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150952-B1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2004-10-27 | — | — | EP | disclosed |