Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 0.40 |
| ▸ | HTR2C | P28335 | 18/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034623 | 0.75 | HTR2A (0.72) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL29956663 | 0.71 | KDM4E (0.53) | HTR2AHTR2CALDH1A1 | |
| SCHEMBL28506409 | 0.70 | MCHR1 (0.48) | L3MBTL1ALDH1A1LMNA | |
| SCHEMBL6034633 | 0.70 | HTR2A (0.60) | HTR2AHTR2CL3MBTL1ALDH1A1GAA | |
| SCHEMBL18828660 | 0.70 | CA2 (0.35) | — | |
| SCHEMBL16625302 | 0.68 | CCR5 (0.51) | — | |
| SCHEMBL29285400 | 0.67 | QDPR (0.54) | — | |
| SCHEMBL16193540 | 0.67 | ENPP2 (0.38) | — | |
| SCHEMBL28506326 | 0.66 | MCHR1 (0.58) | — | |
| SCHEMBL14625146 | 0.64 | DCUN1D1 (0.34) | HTR2AHTR2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414801-A1 | ARYLAMINES FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH GSK-3 | AstraZeneca AB (SE) | 2004-05-06 | — | — | EP | claimed |
| WO-2003004472-A1 | ARYLAMINES FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH GSK-3 | ASTRAZENECA AB (SE) | 2003-01-16 | — | — | WO | claimed |