Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.49 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.45 |
| ▸ | LIPC | P11150 | 1/20 | 0.45 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | GNA15 | P30679 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6601408 | 0.94 | MGLL (0.55) | MGLLFAAHABHD6LPLLIPC | |
| Trifluoroacetic Acid SCHEMBL6601314 | 0.81 | MGLL (0.48) | MGLLFAAHABHD6LPLLIPC | |
| Trifluoroacetic Acid SCHEMBL6601669 | 0.80 | MGLL (0.52) | MGLLFAAHLPLLIPCLIPE | |
| Trifluoroacetic Acid SCHEMBL6602539 | 0.78 | MAPT (0.45) | MGLLFAAHLPLLIPCLIPE | |
| Trifluoroacetic Acid SCHEMBL6601568 | 0.77 | LPL (0.47) | MGLLFAAHLPLLIPCLIPE | |
| Trifluoroacetic Acid SCHEMBL6601748 | 0.75 | FAAH (0.44) | MGLLFAAHLPLLIPCLIPE | |
| Trifluoroacetic Acid SCHEMBL6599045 | 0.75 | MGLL (0.48) | MGLLFAAHABHD6LPLLIPC | |
| Trifluoroacetic Acid SCHEMBL6599708 | 0.75 | LPL (0.46) | MGLLFAAHLPLLIPCLIPE | |
| Trifluoroacetic Acid SCHEMBL6601589 | 0.74 | ABHD16A (0.47) | MGLLFAAHLPLLIPCLIPE | |
| SCHEMBL14044105 | 0.74 | MAPK14 (0.58) | FAAHFFAR1FFAR4GNA15PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |