Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.52 |
| ▸ | FAAH | O00519 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LIPC | P11150 | 2/20 | 0.46 |
| ▸ | LIPE | Q05469 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | LPL | P06858 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6601748 | 0.86 | FAAH (0.44) | MGLLFAAHLIPCLIPEL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL6601568 | 0.85 | LPL (0.47) | MGLLFAAHLIPCLIPEL3MBTL1 | |
| SCHEMBL6600164 | 0.82 | FAAH (0.56) | MGLLFAAHMEN1MAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL6602539 | 0.80 | MAPT (0.45) | MGLLFAAHMEN1GAAMAPT | |
| Trifluoroacetic Acid SCHEMBL6600841 | 0.80 | MGLL (0.50) | MGLLFAAHMEN1KMT2ALIPC | |
| Trifluoroacetic Acid SCHEMBL6604365 | 0.78 | MGLL (0.46) | MGLLFAAHLIPCLIPEBCHE | |
| SCHEMBL6602421 | 0.78 | MGLL (0.54) | MGLLFAAHMAPTLIPCLIPE | |
| Trifluoroacetic Acid SCHEMBL6601368 | 0.76 | MGLL (0.43) | MGLLFAAHMAPTLIPCLIPE | |
| Trifluoroacetic Acid SCHEMBL6602639 | 0.76 | MGLL (0.52) | MGLLFAAHLIPCLIPEBCHE | |
| Trifluoroacetic Acid SCHEMBL6599708 | 0.76 | LPL (0.46) | MGLLFAAHLIPCLIPEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |