Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LIPC | P11150 | 2/20 | 0.44 |
| ▸ | LIPE | Q05469 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6601748 | 0.81 | FAAH (0.44) | LIPCLIPELPLABHD16AL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL6601669 | 0.80 | MGLL (0.52) | MAPTLIPCLIPELPLABHD16A | |
| Trifluoroacetic Acid SCHEMBL6600841 | 0.78 | MGLL (0.50) | KDM4ELIPCLIPELPLABHD16A | |
| Trifluoroacetic Acid SCHEMBL6599708 | 0.77 | LPL (0.46) | LIPCLIPELPLABHD16AL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL6599045 | 0.74 | MGLL (0.48) | LIPCLIPELPLABHD16AFAAH | |
| Trifluoroacetic Acid SCHEMBL6604365 | 0.73 | MGLL (0.46) | LIPCLIPELPLABHD16AFAAH | |
| Trifluoroacetic Acid SCHEMBL6601368 | 0.73 | MGLL (0.43) | MAPTALDH1A1LIPCLIPELPL | |
| Trifluoroacetic Acid SCHEMBL6602042 | 0.72 | LPL (0.46) | LIPCLIPELPLABHD16AFAAH | |
| SCHEMBL11248949 | 0.72 | L3MBTL1 (0.76) | MAPTKDM4EALDH1A1APAF1POLB | |
| Trifluoroacetic Acid SCHEMBL6606875 | 0.71 | MGLL (0.50) | ALDH1A1LIPCLIPELPLABHD16A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |