Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMBS | P08397 | 1/20 | 0.50 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 7/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664245 | 0.82 | — | — | |
| SCHEMBL3164502 | 0.78 | HTT (0.36) | HMBSSPRFLT3ALDH1A1LMNA | |
| SCHEMBL3175020 | 0.77 | SPR (0.34) | HMBSSPRFLT3 | |
| SCHEMBL3551459 | 0.77 | GAA (0.58) | HMBSKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL17624955 | 0.77 | ALOX15 (0.42) | HMBSHPGDPDGFRBPDGFRAGAA | |
| SCHEMBL18900582 | 0.77 | HMBS (0.42) | HMBSSPRKDM4EHPGDHSD17B10 | |
| SCHEMBL1126943 | 0.77 | HMBS (0.42) | HMBSSPRKDM4EHPGDHSD17B10 | |
| SCHEMBL402047 | 0.73 | LMNA (0.51) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL13730301 | 0.69 | PTPN1 (0.58) | HPGDHSD17B10ALDH1A1LMNAALOX15 | |
| SCHEMBL14705586 | 0.69 | IDO1 (0.53) | KDM4EALDH1A1LMNAGAASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150303377-A1 | COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME | U.S. DEPARTMENT OF ENERGY | 2015-10-22 | — | — | US | disclosed |
| US-20150303377-A1 | COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME | U.S. DEPARTMENT OF ENERGY | 2015-10-22 | — | — | US | disclosed |
| US-20150303377-A1 | COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME | U.S. DEPARTMENT OF ENERGY | 2015-10-22 | — | — | US | disclosed |
| EP-2850670-A2 | DIPYRRIN BASED MATERIALS FOR PHOTOVOLTAICS | The Regents of The University of Michigan (US) | 2015-03-25 | — | — | EP | disclosed |
| EP-2740166-A1 | COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME | University of Southern California (US) | 2014-06-11 | — | — | EP | disclosed |
| US-20140076403-A1 | DIPYRIN BASED MATERIALS FOR PHOTOVOLTAICS, COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140076403-A1 | DIPYRIN BASED MATERIALS FOR PHOTOVOLTAICS, COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140076403-A1 | DIPYRIN BASED MATERIALS FOR PHOTOVOLTAICS, COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-03-20 | — | — | US | disclosed |
| WO-2014025435-A2 | DIPYRRIN BASED MATERIALS FOR PHOTOVOLTAICS, COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME | FORREST STEPHEN R (US) | 2014-02-13 | — | — | WO | disclosed |
| WO-2013066453-A1 | COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-05-10 | — | — | WO | disclosed |
| EP-1479384-A1 | FIBROSIS INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6759429-B2 | HAVING TRANSFORMING GROWTH FACTOR- BETA INHIBITORY ACTIVITY AND BEING USEFUL AS FIBROSIS INHIBITORS FOR ORGANS OR TISSUES | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2004-07-06 | — | — | US | disclosed |
| US-20030181496-A1 | Pyrrole derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1310485-A1 | PYRROLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150303377-A1 | COMPOUNDS CAPABLE OF UNDERGOING SYMMETRY BREAKING INTRAMOLECULAR CHARGE TRANSFER IN A POLARIZING MEDIUM AND ORGANIC PHOTOVOLTAIC DEVICES COMPRISING THE SAME | CDH1, RABGGTA, PAX3 | HMBS 259/4885SPR 1882/4885KDM4E 2861/4885 |
| US-20030181496-A1 | Pyrrole derivatives | NCOA1, PKD1, NR3C2 | HMBS 3763/4885SPR 2361/4885KDM4E 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.