Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.60 |
| ▸ | LIPC | P11150 | 1/20 | 0.60 |
| ▸ | LIPE | Q05469 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 5/20 | 0.54 |
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602288 | 0.79 | LPL (0.57) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL6601946 | 0.77 | LPL (0.57) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL6600164 | 0.77 | FAAH (0.56) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL7043932 | 0.76 | LPL (0.56) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL7047919 | 0.75 | LPL (1.00) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL11620781 | 0.75 | FAAH (0.78) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL6600553 | 0.74 | LPL (0.62) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL6603509 | 0.74 | LPL (0.56) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL7650640 | 0.74 | LPL (0.56) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL6604889 | 0.73 | LPL (0.72) | LPLLIPCLIPEMGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |