Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.57 |
| ▸ | LIPC | P11150 | 1/20 | 0.57 |
| ▸ | LIPE | Q05469 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 5/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | ABHD16A | O95870 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603090 | 0.79 | LPL (0.60) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL7319761 | 0.77 | MAPT (0.60) | ENPP2MAPTTP53THRBPOLB | |
| SCHEMBL7321052 | 0.77 | MAPT (0.60) | ENPP2MAPTTP53THRBPOLB | |
| SCHEMBL6604889 | 0.75 | LPL (0.72) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL11620781 | 0.73 | FAAH (0.78) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL6602316 | 0.72 | LPL (0.64) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL7650640 | 0.71 | LPL (0.56) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL7040935 | 0.70 | ABHD16A (0.68) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL6603509 | 0.70 | LPL (0.56) | LPLLIPCLIPEMGLLFAAH | |
| SCHEMBL6603513 | 0.69 | LPL (0.64) | LPLLIPCLIPEMGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263745-B1 | SUBSTITUTED 3-PHENYL-5-ALKOXI-1,3,4-OXDIAZOL-2-ONE AND USE THEREOF FOR INHIBITING HORMONE-SENSITIVE LIPASE | AVENTIS PHARMA GMBH (DE) | 2004-05-19 | — | — | EP | disclosed |