Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27854995 | 0.90 | ALDH1A1 (0.41) | ALDH1A1RAB9ASMN1; SMN2MGAMAMY1A | |
| SCHEMBL298474 | 0.86 | SMN1; SMN2 (0.40) | ALDH1A1RAB9ASMN1; SMN2MGAMAMY1A | |
| SCHEMBL660154 | 0.85 | SMN1; SMN2 (0.39) | ALDH1A1RAB9ASMN1; SMN2MGAMAMY1A | |
| SCHEMBL27871677 | 0.85 | ALDH1A1 (0.38) | ALDH1A1RAB9ASMN1; SMN2MGAMAMY1A | |
| SCHEMBL658507 | 0.83 | TSHR (0.42) | ALDH1A1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL287206 | 0.83 | PTGS2 (0.47) | ALDH1A1SMN1; SMN2GAAHPGDKDM4E | |
| SCHEMBL7805087 | 0.81 | HDAC1 (0.40) | ALDH1A1RAB9ASMN1; SMN2MGAMAMY1A | |
| SCHEMBL27854950 | 0.81 | ADRA2C (0.35) | ALDH1A1RAB9ASMN1; SMN2MGAMAMY1A | |
| SCHEMBL660680 | 0.80 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2GSK3AGSK3BHPGD | |
| SCHEMBL660364 | 0.80 | PDCD1 (0.43) | ALDH1A1RAB9ASMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | ALDH1A1 676/4885RAB9A 2179/4885SMN1; SMN2 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.