Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.32 |
| ▸ | PAK4 | O96013 | 3/20 | 0.32 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.32 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16503534 | 0.83 | CES2 (0.35) | CES2ARMAPTTAS2R14MGLL | |
| SCHEMBL7997120 | 0.74 | TAS2R14 (0.47) | CES2MAPTTAS2R14RAPGEF4 | |
| SCHEMBL19720165 | 0.72 | GABRA1 (0.36) | ARMAPTASIC3MAP3K14PAK4 | |
| SCHEMBL13692781 | 0.71 | ASIC3 (0.34) | MAPTASIC3KMT2AMAP3K14PAK4 | |
| SCHEMBL2858168 | 0.71 | MAPT (0.38) | MAPTASIC3MEN1KMT2AMAP3K14 | |
| SCHEMBL4564009 | 0.71 | CES2 (0.48) | CES2ARMAPTMEN1KMT2A | |
| SCHEMBL7216715 | 0.71 | CES2 (0.48) | CES2ARMAPTMEN1KMT2A | |
| SCHEMBL12391039 | 0.71 | ASIC3 (0.50) | MAPTASIC3KMT2AMAP3K14PIKFYVE | |
| SCHEMBL5540303 | 0.70 | CES2 (0.38) | CES2MAPTTAS2R14RAPGEF4 | |
| SCHEMBL19385736 | 0.69 | GABRA1 (0.34) | CES2MAPTTAS2R14RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219173-B1 | INSECTICIDES AND ACARICIDES | AGRO KANESHO CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-20030191171-A1 | Pyrazolyl compound | AGRO-KANESHO CO., LTD. (JP) | 2003-10-09 | — | — | US | disclosed |
| US-20020156115-A1 | Insecticidal and acaricidal composition, and methods of using the same | AGRO-KANESHO CO., LTD. (JP) | 2002-10-24 | — | — | US | disclosed |
| EP-1219173-A1 | INSECTICIDAL AND ACARICIDAL AGENTS | Agro-Kanesho Co., Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156115-A1 | Insecticidal and acaricidal composition, and methods of using the same | GSTO1, CBR3, CBR1 | CES2 501/4885AR 1360/4885MAPT 4877/4885 |
| US-20030191171-A1 | Pyrazolyl compound | GSTO1, CBR3, GSTM1 | CES2 963/4885AR 923/4885MAPT 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.