Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.49 |
| ▸ | GNPAT | O15228 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249331 | 1.00 | NOD1 (0.49) | NOD1GNPATFOLH1NAALAD2RIMKLA | |
| SCHEMBL15401429 | 0.92 | NOD1 (0.51) | NOD1GNPAT | |
| SCHEMBL7918137 | 0.84 | NOD1 (0.39) | NOD1GNPAT | |
| SCHEMBL1373235 | 0.81 | ALDH1A1 (0.36) | NAALAD2 | |
| SCHEMBL2467621 | 0.80 | BHMT (0.48) | NOD1FOLH1 | |
| SCHEMBL28727840 | 0.77 | FOLH1 (0.56) | NOD1GNPATFOLH1NAALAD2RIMKLA | |
| SCHEMBL29517639 | 0.77 | FOLH1 (0.56) | NOD1GNPATFOLH1NAALAD2RIMKLA | |
| SCHEMBL28727831 | 0.77 | FOLH1 (0.56) | NOD1GNPATFOLH1NAALAD2RIMKLA | |
| SCHEMBL23044064 | 0.76 | FOLH1 (0.60) | NOD1FOLH1NAALAD2RIMKLA | |
| SCHEMBL2490631 | 0.76 | FOLH1 (0.60) | NOD1FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046329-A1 | MODULATORS OF NOD1 AND NOD2 SIGNALING, METHODS OF IDENTIFYING MODULATORS OF NOD1 AND NOD2 SIGNALING, AND USES THEREOF | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046329-A1 | MODULATORS OF NOD1 AND NOD2 SIGNALING, METHODS OF IDENTIFYING MODULATORS OF NOD1 AND NOD2 SIGNALING, AND USES THEREOF | NOD2, NOD1, NLRP1 | NOD1 2/4885GNPAT 3806/4885FOLH1 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.