Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.49 |
| ▸ | HTR5A | P47898 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609224 | 0.85 | HTR6 (0.53) | HTR6ADRB1HTR5AHTR7HTR3E | |
| SCHEMBL4173685 | 0.77 | HTR6 (0.56) | HTR6ADRB1HTR5AHTR7HTR3E | |
| SCHEMBL6607017 | 0.77 | HTR6 (0.54) | HTR6ADRB1HTR5AHTR7HTR3E | |
| SCHEMBL8654792 | 0.74 | HTR6 (0.51) | HTR6ADRB1HTR5AHTR7HTR3E | |
| SCHEMBL6607018 | 0.74 | HTR6 (0.53) | HTR6ADRB1HTR5AHTR7HTR3E | |
| SCHEMBL9214113 | 0.73 | HTR5A (0.45) | HTR6ADRB1HTR5AHTR7HTR3E | |
| Hydrochloric Acid SCHEMBL6017183 | 0.72 | LMNA (0.46) | HTR6ADRB1HTR5AHTR7HTR3E | |
| SCHEMBL21291592 | 0.71 | ADRB1 (0.56) | HTR6ADRB1HTR5AHTR7HTR3E | |
| SCHEMBL30516390 | 0.71 | ADRB1 (0.56) | HTR6ADRB1HTR5AHTR7HTR3E | |
| SCHEMBL612522 | 0.71 | HTR1A (0.68) | HTR6ADRB1HTR7HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432701-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003031436-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF DISORDERS OF THE URINARY TRACT | RECORDATI S.A. (CH) | 2003-04-17 | — | — | WO | disclosed |