Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779981 | 0.76 | RAB9A (0.53) | FAAHCES1NCEH1HDAC3HDAC4 | |
| SCHEMBL3759507 | 0.75 | HDAC6 (0.51) | CES1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6607872 | 0.74 | HDAC3 (0.42) | FAAHCES1NCEH1HDAC3HDAC4 | |
| SCHEMBL6609769 | 0.74 | RAB9A (0.58) | NPC1CYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL27705691 | 0.74 | FAAH (0.44) | FAAHCES1NCEH1HDAC3HDAC4 | |
| SCHEMBL3759873 | 0.72 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL429187 | 0.71 | PTPN1 (0.48) | HDAC3HDAC1HDAC7HDAC2HDAC8 | |
| SCHEMBL3759725 | 0.71 | EGLN2 (0.49) | NPC1RAB9A | |
| SCHEMBL7361889 | 0.71 | CASP3 (0.54) | HDAC3HDAC1NPC1CYP1A2RAB9A | |
| SCHEMBL5607153 | 0.70 | LMNA (0.59) | HDAC3HDAC1HDAC2HDAC6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266826-A1 | Thiophenylthiopyrane dioxides as mmp or tnf-alpha inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-30 | — | — | US | claimed |
| EP-1423386-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | claimed |
| WO-2003022842-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266826-A1 | Thiophenylthiopyrane dioxides as mmp or tnf-alpha inhibitors | TNF, MMP9, MMP1 | FAAH 1088/4885CES1 180/4885NCEH1 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.