Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11368795 | 0.80 | P2RX3 (0.41) | HSD17B14F2F10PRSS1PRSS2 | |
| SCHEMBL11275809 | 0.77 | ALDH1A1 (0.47) | HSD17B14F2F10PRSS1PRSS2 | |
| SCHEMBL10871695 | 0.77 | FFAR1 (0.53) | HSD17B14F2F10PRSS1PRSS2 | |
| SCHEMBL10653082 | 0.75 | KDM4E (0.44) | HSD17B14 | |
| SCHEMBL11275806 | 0.74 | L3MBTL1 (0.43) | HSD17B14F2F10PRSS1PRSS2 | |
| SCHEMBL10841713 | 0.74 | F2 (0.44) | HSD17B14F2F10PRSS1PRSS2 | |
| SCHEMBL11393045 | 0.74 | MTNR1A (0.38) | ALOX5PTGS1HSD17B14F2F10 | |
| SCHEMBL11175776 | 0.74 | KCNH2 (0.44) | HSD17B14F2F10PRSS1PRSS2 | |
| SCHEMBL9198043 | 0.74 | KCNH2 (0.44) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL2893839 | 0.74 | F2 (0.46) | HSD17B14F2F10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794336-B2 | Herbicidal substituted pyridines, their preparation, and their use as herbicides and plant growth regulators | AVENTIS CROP SCIENCE GMBH (DE) | 2004-09-21 | — | — | US | claimed |
| EP-1401827-A2 | HERBICIDAL SUBSTITUTED PYRIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDAL AGENTS AND PLANT GROWTH REGULATORS | Bayer CropScience GmbH (DE) | 2004-03-31 | — | — | EP | claimed |
| US-20030229125-A1 | Herbicidal substituted pyridines, their preparation, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2003-12-11 | — | — | US | claimed |
| WO-2003000679-A2 | HERBICIDAL SUBSTITUTED PYRIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDAL AGENTS AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2003-01-03 | — | — | WO | claimed |
| US-6794336-B2 | Herbicidal substituted pyridines, their preparation, and their use as herbicides and plant growth regulators | AVENTIS CROP SCIENCE GMBH (DE) | 2004-09-21 | — | — | US | disclosed |
| CN-1520407-A | Herbicidally substituted pyridines, their preparation and their use as herbicides and plant growth regulators | �Ϻ���ͨ��ѧ | 2004-08-11 | — | — | CN | disclosed |
| EP-1401827-A2 | HERBICIDAL SUBSTITUTED PYRIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDAL AGENTS AND PLANT GROWTH REGULATORS | Bayer CropScience GmbH (DE) | 2004-03-31 | — | — | EP | disclosed |
| EP-1401827-A2 | HERBICIDAL SUBSTITUTED PYRIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDAL AGENTS AND PLANT GROWTH REGULATORS | Bayer CropScience GmbH (DE) | 2004-03-31 | — | — | EP | disclosed |
| US-20030229125-A1 | Herbicidal substituted pyridines, their preparation, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2003-12-11 | — | — | US | disclosed |
| US-20030229125-A1 | Herbicidal substituted pyridines, their preparation, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2003-12-11 | — | — | US | disclosed |
| WO-2003000679-A3 | HERBICIDAL SUBSTITUTED PYRIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDAL AGENTS AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2003-04-24 | — | — | WO | disclosed |
| WO-2003000679-A2 | HERBICIDAL SUBSTITUTED PYRIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDAL AGENTS AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000679-A2 | HERBICIDAL SUBSTITUTED PYRIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDAL AGENTS AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2003-01-03 | — | — | WO | disclosed |
| EP-0196184-B1 | ARYL DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-09-16 | — | — | EP | disclosed |
| US-5036157-A | Hydroxamic acid derivatives, lipoxygenase and cyclooxygenase inhibitors, anticoagulants, antiinflammatory agents | BURROUGHS WELLCOME CO. | 1991-07-30 | — | — | US | disclosed |
| US-4977188-A | Hydroamic acid derivatives | BURROUGHS WELLCOME CO. (US) | 1990-12-11 | — | — | US | disclosed |
| WO-1990001929-A1 | NEW MEDICAL USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-03-08 | — | — | WO | disclosed |
| US-4738986-A | CYCLOOXYGENASE, LIDOXYGENASE INHIBITORS | BURROUGHS WELLCOME CO. (US) | 1988-04-19 | — | — | US | disclosed |
| EP-0196184-A2 | Aryl derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229125-A1 | Herbicidal substituted pyridines, their preparation, and their use as herbicides and plant growth regulators | CBR3, CBR1, CYCS | ALOX5 1388/4885PTGS1 916/4885PTGS2 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.