Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.52 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.52 |
| ▸ | ASIC3 | Q9UHC3 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493590 | 0.84 | RAB9A (0.62) | SMARCA2SMARCA4PBRM1RAB9ANPC1 | |
| SCHEMBL28677979 | 0.81 | APP (0.46) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL13458070 | 0.79 | RAB9A (0.58) | SMARCA2SMARCA4PBRM1RAB9ANPC1 | |
| SCHEMBL2462546 | 0.79 | LMNA (0.43) | RAB9ANPC1PKMSMN1; SMN2TP53 | |
| SCHEMBL22545493 | 0.79 | BCAT2 (0.39) | SMARCA2SMARCA4PBRM1RAB9ANPC1 | |
| SCHEMBL16598334 | 0.77 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL1752781 | 0.77 | SLC6A2 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29393106 | 0.77 | SLC6A2 (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29392176 | 0.77 | LTA4H (0.47) | RAB9ANPC1PKMSMN1; SMN2USP2 | |
| SCHEMBL16848044 | 0.77 | METAP2 (0.39) | SMARCA2SMARCA4PBRM1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264014-A1 | Substituted pyridazines as anti-inflammatory agents and protein kinase inhibitors | Université Louis Pasteur (FR) | 2010-12-22 | — | — | EP | claimed |
| EP-0306408-B1 | Imidazo[1,2,-b]pyridazines, process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1992-03-18 | — | — | EP | claimed |
| EP-0225886-B1 | NEW PYRIDAZINE COMPOSITIONS, PRODUCTION PROCESS THEREOF AND FUNGICIDES AND ALGICIDES CONTAINING THEM | AGROLINZ AGRARCHEMIKALIEN GESELLSCHAFT M.B.H. (AT) | 1990-06-20 | — | — | EP | claimed |
| EP-0225886-A1 | NEW PYRIDAZINE COMPOSITIONS, PRODUCTION PROCESS THEREOF AND FUNGICIDES AND ALGICIDES CONTAINING THEM. | CHEMIE LINZ AG (AT) | 1987-06-24 | — | — | EP | claimed |
| WO-1986006719-A1 | NEW PYRIDAZINE COMPOSITIONS, PRODUCTION PROCESS THEREOF AND FUNGICIDES AND ALGICIDES CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-11-20 | — | — | WO | claimed |
| JP-1071877-A | — | — | None | — | — | JP | disclosed |
| EP-4069243-B1 | COMBINATIONS OF ETC-159 AND OLAPARIB FOR USE IN THE TREATMENT OF PANCREATIC CANCER, OVARIAN CANCER AND CHOLANGIO-CARCINOMAS | AGENCY SCIENCE TECH & RES (SG) | 2026-04-01 | — | — | EP | disclosed |
| US-12559495-B2 | Purine diones as Wnt pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2026-02-24 | — | — | US | disclosed |
| EP-4559908-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | S2CBio Inc. (KR) | 2025-05-28 | — | — | EP | disclosed |
| US-11993595-B2 | Compounds | MISSION THERAPEUTICS LIMITED (GB) | 2024-05-28 | — | — | US | disclosed |
| WO-2024058617-A1 | ANTIVIRAL USE OF HETEROARYL DERIVATIVE COMPOUND | 일동제약(주) | 2024-03-21 | — | — | WO | disclosed |
| WO-2024019541-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-25 | — | — | WO | disclosed |
| EP-0510562-A1 | Pyridazines | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1992-10-28 | — | — | EP | disclosed |
| EP-0225886-B1 | NEW PYRIDAZINE COMPOSITIONS, PRODUCTION PROCESS THEREOF AND FUNGICIDES AND ALGICIDES CONTAINING THEM | AGROLINZ AGRARCHEMIKALIEN GESELLSCHAFT M.B.H. (AT) | 1990-06-20 | — | — | EP | disclosed |
| EP-0225886-B1 | NEW PYRIDAZINE COMPOSITIONS, PRODUCTION PROCESS THEREOF AND FUNGICIDES AND ALGICIDES CONTAINING THEM | AGROLINZ AGRARCHEMIKALIEN GESELLSCHAFT M.B.H. (AT) | 1990-06-20 | — | — | EP | disclosed |
| US-4910199-A | Substituted with a phenyl ring | SANOFI (FR) | 1990-03-20 | — | — | US | disclosed |
| EP-0225886-A1 | NEW PYRIDAZINE COMPOSITIONS, PRODUCTION PROCESS THEREOF AND FUNGICIDES AND ALGICIDES CONTAINING THEM. | CHEMIE LINZ AG (AT) | 1987-06-24 | — | — | EP | disclosed |
| EP-0225886-A1 | NEW PYRIDAZINE COMPOSITIONS, PRODUCTION PROCESS THEREOF AND FUNGICIDES AND ALGICIDES CONTAINING THEM. | CHEMIE LINZ AG (AT) | 1987-06-24 | — | — | EP | disclosed |
| WO-1986006719-A1 | NEW PYRIDAZINE COMPOSITIONS, PRODUCTION PROCESS THEREOF AND FUNGICIDES AND ALGICIDES CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-11-20 | — | — | WO | disclosed |
| WO-1986006719-A1 | NEW PYRIDAZINE COMPOSITIONS, PRODUCTION PROCESS THEREOF AND FUNGICIDES AND ALGICIDES CONTAINING THEM | CHEMIE LINZ AKTIENGESELLSCHAFT (AT) | 1986-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11993595-B2 | Compounds | UCHL1, UCHL3, UCHL5 | SMARCA2 2727/4885SMARCA4 2393/4885PBRM1 562/4885 |
| US-12559495-B2 | Purine diones as Wnt pathway modulators | WNT1, CTNND1, WNT3A | SMARCA2 1384/4885SMARCA4 1394/4885PBRM1 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.