Sugi Predict

Sugi Predict / Compounds / SCHEMBL69333

SCHEMBL69333

SCHEMBL69333

Nc1ccc(-c2ccccc2)nc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LDHA P00338 1/20 0.52
▸ ASIC3 Q9UHC3 3/20 0.50
▸ TLR9 Q9NR96 1/20 0.50
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ TAAR1 Q96RJ0 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.48
▸ CYP11B1 P15538 4/20 0.46
▸ CYP11B2 P19099 4/20 0.46
▸ HPGDS O60760 1/20 0.46
▸ ADORA2A P29274 2/20 0.45
▸ AURKA O14965 1/20 0.45
▸ HSP90AA1 P07900 1/20 0.45
▸ PRKACA P17612 1/20 0.45
▸ ADORA1 P30542 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29605039 1.00 LDHA (0.52) LDHAASIC3TLR9MEN1KMT2A
SCHEMBL15614080 0.96 HSD17B10 (0.56) LDHAASIC3TLR9MEN1KMT2A
SCHEMBL30337692 0.88 METAP2 (0.45) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL8974216 0.88 METAP2 (0.45) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL14988250 0.86 MAOA (0.50) LDHAASIC3TLR9MEN1KMT2A
SCHEMBL30087143 0.86 METAP2 (0.48) ASIC3MEN1KMT2AALDH1A1MAPT
SCHEMBL6804411 0.86 METAP2 (0.48) ASIC3MEN1KMT2AALDH1A1MAPT
SCHEMBL18745783 0.85 HSD17B10 (0.60) LDHAASIC3TLR9MEN1KMT2A
SCHEMBL18745782 0.85 HSD17B10 (0.60) LDHAASIC3TLR9MEN1KMT2A
SCHEMBL14988406 0.84 ALOX5AP (0.44) ASIC3TLR9MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974067-A High-thermal-conductivity graphite film of pyridine ring modified polyimide and preparation method thereof 富优特(山东)新材料科技有限公司 2023-04-18 — — CN claimed
US-6448205-B1 FOR THE DESICCATION AND/OR DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2002-09-10 — — US claimed
EP-0920415-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1999-06-09 — — EP claimed
WO-1998007700-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1998-02-26 — — WO claimed
EP-4638445-A1 1,2,4-THIAZOLIDIN-3-ONE-1,1-DIOXIDE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE Bristol-Myers Squibb Company (US) 2025-10-29 — — EP disclosed
US-12391663-B2 Isoindolinone compounds MONTE ROSA THERAPEUTICS AG (CH) 2025-08-19 — — US disclosed
CN-119733563-A Preparation method of modified carbon nano tube metal catalyst 无锡六号元素新材料科技有限公司 2025-04-01 — — CN disclosed
US-20240261274-A1 TREATMENT OF MYC-DRIVEN CANCERS WITH GSPT1 DEGRADERS MONTE ROSA THERAPEUTICS AG (CH) 2024-08-08 — — US disclosed
US-20240228476-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-11 — — US disclosed
US-20240216355-A1 PHARMACEUTICAL COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF A DISEASE OR DISORDER CAUSED BY OR ASSOCIATED WITH ONE OR MORE PREMATURE TERMINATION CODONS MONTE ROSA THERAPEUTICS AG (CH) 2024-07-04 — — US disclosed
WO-2024137727-A1 1,2,4-THIAZOLIDIN-3-ONE-1,1-DIOXIDE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY (US) 2024-06-27 — — WO disclosed
US-11993595-B2 Compounds MISSION THERAPEUTICS LIMITED (GB) 2024-05-28 — — US disclosed
EP-1140847-B1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AG (DE) 2002-12-18 — — EP disclosed
US-6448205-B1 FOR THE DESICCATION AND/OR DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2002-09-10 — — US disclosed
US-6432880-B1 APPLYING TO PLANTS BASF AKTIENGESELLSCHAFT (DE) 2002-08-13 — — US disclosed
CN-1336918-A Substituted 2-phenylpyridines as herbicides BASF AG (DE) 2002-02-20 — — CN disclosed
EP-1140847-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-10-10 — — EP disclosed
WO-2000042015-A1 SUBSTITUTED 2-PHENYLPYRIDINES AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-07-20 — — WO disclosed
EP-0920415-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1999-06-09 — — EP disclosed
WO-1998007700-A1 SUBSTITUTED 2-PHENYLPYRIDINE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1998-02-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228476-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE PTPN2, PTPN22, PTPN1 LDHA 4461/4885ASIC3 3135/4885TLR9 4121/4885
US-12391663-B2 Isoindolinone compounds CYP4F2, AOC2, AOC3 LDHA 2923/4885ASIC3 1390/4885TLR9 4788/4885
US-20240216355-A1 PHARMACEUTICAL COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF A DISEASE OR DISORDER CAUSED BY OR ASSOCIATED WITH ONE OR MORE PREMATURE TERMINATION CODONS UPF1, NSUN2, RTF2 LDHA 4164/4885ASIC3 2665/4885TLR9 4391/4885
US-11993595-B2 Compounds UCHL1, UCHL3, UCHL5 LDHA 2269/4885ASIC3 4124/4885TLR9 3973/4885
US-20240261274-A1 TREATMENT OF MYC-DRIVEN CANCERS WITH GSPT1 DEGRADERS MYC, MYCBP, GSPT1 LDHA 3833/4885ASIC3 4281/4885TLR9 4295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.