Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.54 |
| ▸ | CA1 | P00915 | 12/20 | 0.54 |
| ▸ | CA9 | Q16790 | 8/20 | 0.54 |
| ▸ | CA12 | O43570 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | FGB | P02675 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660154 | 0.81 | SMN1; SMN2 (0.39) | CA12KMT2AMEN1MAPTGAA | |
| SCHEMBL298474 | 0.79 | SMN1; SMN2 (0.40) | CA12KMT2AMEN1MAPTCTDSP1 | |
| SCHEMBL658725 | 0.78 | POLB (0.46) | CA2CA1CA9KMT2AMEN1 | |
| SCHEMBL660454 | 0.78 | KAT6A (0.51) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL660917 | 0.77 | ALDH1A1 (0.40) | CA12KMT2AMEN1MAPTGAA | |
| SCHEMBL287206 | 0.77 | PTGS2 (0.47) | KMT2AMEN1MAPTCYP2C9CYP2C19 | |
| SCHEMBL660526 | 0.76 | KAT6A (0.35) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL298933 | 0.76 | RAB9A (0.40) | CA12KMT2AMEN1POLBMAPT | |
| SCHEMBL658510 | 0.76 | POLB (0.47) | KMT2AMEN1POLBMAPTNPSR1 | |
| SCHEMBL27854995 | 0.75 | ALDH1A1 (0.41) | CA12KMT2AMEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | CA2 3360/4885CA1 4734/4885CA9 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.