Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623086 | 0.68 | RAB9A (0.36) | SMN1; SMN2RAB9ALMNAL3MBTL1 | |
| Ethyl Isonipecotate SCHEMBL27818566 | 0.68 | PKM (0.54) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL6620194 | 0.67 | CYP1A2 (0.37) | ALDH1A1KDM4EHPGDTSHRMEN1 | |
| SCHEMBL7081699 | 0.66 | TACR3 (0.38) | ALDH1A1KDM4EMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL6183908 | 0.66 | ACACB (0.61) | KDM4EMAPK1SMN1; SMN2GAANPSR1 | |
| SCHEMBL6185100 | 0.66 | ACACB (0.61) | KDM4EMAPK1SMN1; SMN2GAANPSR1 | |
| SCHEMBL3459037 | 0.66 | ACACB (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNAHPGD | |
| Ethyl Isonipecotate SCHEMBL9733648 | 0.66 | MAPT (0.48) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL5063121 | 0.65 | RAB9A (0.61) | ALDH1A1KDM4EMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL3476143 | 0.63 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2TSHRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-A1 | ACC INHIBITORS | Pfizer Products Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072197-A1 | ACC INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | disclosed |