Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 7/20 | 0.35 |
| ▸ | ACACA | Q13085 | 7/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623086 | 0.85 | RAB9A (0.36) | ACACBACACAHTR3EHTR3BHTR3A | |
| SCHEMBL6492751 | 0.83 | LMNA (0.32) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL6620762 | 0.81 | CCR1 (0.41) | CYP1A2KDM4EMEN1ALDH1A1CYP2C19 | |
| SCHEMBL6624779 | 0.67 | ALDH1A1 (0.40) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL6499458 | 0.66 | FASN (0.39) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL6621919 | 0.64 | OPRD1 (0.38) | ACACBACACACCR1SLC6A4 | |
| SCHEMBL23216109 | 0.61 | HTR3E (0.49) | MEN1HPGDKMT2AHTR3EHTR3B | |
| SCHEMBL29745519 | 0.61 | HTR3E (0.49) | MEN1HPGDKMT2AHTR3EHTR3B | |
| SCHEMBL5617165 | 0.60 | — | — | |
| SCHEMBL6860747 | 0.59 | GABRA5 (0.40) | MEN1KMT2AGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478437-A1 | ACC INHIBITORS | Pfizer Products Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072197-A1 | ACC INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | disclosed |