Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LSS | P48449 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184351 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1MAPTTHRBKCNA5 | |
| SCHEMBL6624933 | 0.81 | DRD2 (0.56) | KDM4EALDH1A1MAPTTHRBKCNA5 | |
| SCHEMBL9513241 | 0.78 | THRB (0.82) | KDM4EALDH1A1MAPTTHRBKCNA5 | |
| SCHEMBL9512997 | 0.78 | THRB (0.73) | KDM4EALDH1A1MAPTTHRBKCNA5 | |
| SCHEMBL5242494 | 0.77 | KCNA5 (0.55) | KDM4EALDH1A1MAPTTHRBKCNA5 | |
| SCHEMBL5240284 | 0.77 | KCNA5 (0.55) | KDM4EALDH1A1MAPTTHRBKCNA5 | |
| SCHEMBL9513046 | 0.77 | HTR2A (0.60) | KDM4EALDH1A1MAPTTHRBPOLB | |
| SCHEMBL5240107 | 0.76 | KCNA5 (0.54) | KDM4EALDH1A1MAPTTHRBKCNA5 | |
| Hydrochloric Acid SCHEMBL9512919 | 0.76 | HTR2A (0.58) | KDM4EALDH1A1MAPTTHRBPOLB | |
| SCHEMBL5242861 | 0.76 | KCNA5 (0.51) | KDM4EALDH1A1MAPTTHRBKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389189-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION (US) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094799-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION (US) | 2002-11-28 | — | — | WO | disclosed |