Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625499 | 0.72 | HTR1A (0.31) | CNR1MAPTPOLB | |
| SCHEMBL6626884 | 0.68 | HTT (0.46) | MAPTPARP1KDM4EMEN1LMNA | |
| SCHEMBL6626394 | 0.66 | PARP1 (0.68) | MAPTPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL8824064 | 0.62 | KDM4E (0.40) | MAPTPARP1KDM4EALDH1A1HPGD | |
| SCHEMBL10164853 | 0.62 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1HPGDGAA | |
| SCHEMBL30067500 | 0.61 | TYMS (0.37) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL8557216 | 0.61 | NOTUM (0.44) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL6622604 | 0.60 | HTT (0.44) | PARP1PGR | |
| SCHEMBL6623903 | 0.60 | HTT (0.44) | PARP1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL11112840 | 0.60 | NOTUM (0.35) | MAPTPOLBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |