Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78185 | 0.86 | PDK1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL64034 | 0.73 | CHRM5 (0.38) | ALDH1A1MAPT | |
| SCHEMBL18586543 | 0.73 | MEN1 (0.37) | ALDH1A1MAPTADORA1 | |
| SCHEMBL3992432 | 0.69 | ADORA1 (0.37) | ALDH1A1MAPTADORA1 | |
| SCHEMBL64675 | 0.69 | PDK1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL66293 | 0.68 | PPM1B (0.32) | — | |
| SCHEMBL27097345 | 0.67 | MEN1 (0.36) | ALDH1A1MAPTADORA1 | |
| SCHEMBL19078526 | 0.67 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL1082333 | 0.66 | ESR1 (0.39) | ALDH1A1MAPTADORA1 | |
| SCHEMBL65230 | 0.66 | MAPT (0.33) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |