Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21847545 | 0.74 | MEN1 (0.38) | MAPTHSD17B10ALDH1A1TSHRLMNA | |
| SCHEMBL67381 | 0.73 | MAPT (0.40) | MAPTHSD17B10ALDH1A1LMNANPEPPS | |
| SCHEMBL66293 | 0.73 | PPM1B (0.32) | — | |
| SCHEMBL2350221 | 0.71 | NFKB1 (0.38) | MAPTHSD17B10ALDH1A1TSHRNPEPPS | |
| SCHEMBL16077029 | 0.70 | ALDH1A1 (0.35) | MAPTHSD17B10ALDH1A1TSHRNPSR1 | |
| SCHEMBL30800899 | 0.70 | FKBP1A (0.32) | FKBP1A | |
| SCHEMBL25282754 | 0.69 | PPM1D (0.34) | HSD17B10ALDH1A1LMNAFKBP1A | |
| SCHEMBL17674517 | 0.69 | PPM1D (0.34) | HSD17B10ALDH1A1LMNAFKBP1A | |
| SCHEMBL30742994 | 0.69 | LMNA (0.33) | HSD17B10ALDH1A1TSHRLMNAMEN1 | |
| SCHEMBL22443334 | 0.69 | RIPK1 (0.32) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |