Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65230 | 0.73 | MAPT (0.33) | — | |
| SCHEMBL64035 | 0.72 | SLC6A2 (0.37) | — | |
| SCHEMBL30800899 | 0.70 | FKBP1A (0.32) | — | |
| SCHEMBL31603249 | 0.70 | TACR1 (0.36) | — | |
| SCHEMBL31603373 | 0.70 | TACR1 (0.36) | — | |
| SCHEMBL31603489 | 0.68 | — | — | |
| SCHEMBL66292 | 0.68 | ALDH1A1 (0.35) | — | |
| SCHEMBL368178 | 0.68 | PPM1B (0.39) | PPM1BPTPN1PPP1CC | |
| SCHEMBL25282754 | 0.67 | PPM1D (0.34) | — | |
| SCHEMBL17674517 | 0.67 | PPM1D (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |