Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL663144

C1=C\CC/C=C\CC/1.C1=C\CC/C=C\CC/1.O=S(=O)([O-])C(F)(F)F.[Rh+]

nearest known ligand 0.39

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.39
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
ACHE P22303 2/20 0.32
KCNH2 Q12809 6/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL29253571 1.00 GPR3 (0.39) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL663145 1.00 GPR3 (0.39) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL9109080 1.00 GPR3 (0.39) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL3682796 0.94 GPR3 (0.39) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL9692462 0.94 GPR3 (0.39) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL204687 0.94 GPR3 (0.39) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL529510 0.94 GPR3 (0.39) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL2301332 0.94 GPR3 (0.39) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL9692471 0.94 GPR3 (0.39) GPR3CA1CA2CA7CA13
Trifluoromethanesulfonic Acid SCHEMBL29391563 0.94 GPR3 (0.39) GPR3CA1CA2CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4486730-A1 PROCESSES FOR THE PREPARATION OF PHENYLTETRAHYDROFURAN COMPOUNDS Genentech Inc. (US) 2025-01-08 EP claimed
WO-2023164679-A1 PROCESSES FOR THE PREPARATION OF PHENYLTETRAHYDROFURAN COMPOUNDS GENENTECH, INC. (US) 2023-08-31 WO claimed
US-10975085-B2 Process for preparing a composition comprising an enantiomeric excess of greater than or equal to 90% of the (R)-enantiomer of a compound of formula III INCYTE HOLDINGS CORPORATION (US) 2021-04-13 US claimed
WO-2017044043-A1 PROCESS FOR DIRECT AMIDATION OF AMINES VIA RH(I)-CATALYZED ADDITION OF BOROXINES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-03-16 WO claimed
US-20110288297-A1 Pyrrolo[2,3-d]Pyrimidine Derivatives; Their Intermediates and Synthesis PFIZER, INC. (US) 2011-11-24 US claimed
EP-1913000-A2 PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES; THEIR INTERMEDIATES AND SYNTHESIS Pfizer Products Inc. (US) 2008-04-23 EP claimed
WO-2007012953-A2 PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES; THEIR INTERMEDIATES AND SYNTHESIS PFIZER PRODUCTS INC. (US) 2007-02-01 WO claimed
EP-3541825-B1 CYCLIC PHOSPHATE SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF LIVER DISEASES IDENIX PHARMACEUTICALS LLC (US) 2026-04-01 EP disclosed
US-12559504-B2 Benzotriazole derivative UBE CORPORATION (JP) 2026-02-24 US disclosed
US-RE50724-E1 4-membered ring carboxamides used as nematicides SYNGENTA CROP PROTECTION AG (CH) 2026-01-06 US disclosed
EP-3978073-B1 1H-BENZO[D][1,2,3]TRIAZOLE DERIVATIVES AS KEAP1 INHIBITORS FOR THE TREATMENT OF RENAL DISEASES UBE CORP (JP) 2025-10-15 EP disclosed
US-20250122160-A1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF CALICO LIFE SCIENCES LLC (US) 2025-04-17 US disclosed
US-12129249-B2 Method for producing optically active compound DAY ONE BIOPHARMACEUTICALS, INC. (US) 2024-10-29 US disclosed
US-6242377-B1 POLYMERIZATION IN PRESENCE OF BISOXAZOLINE WITH NICKEL, COBALT, PALLADIUM, RHODIUM, RUTHENIUM, ALUMINUM AND BORON COMPLEXES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-05 US disclosed
EP-1063226-A1 Process for the preparation of N-acyl-amino acids Degussa-Hüls Aktiengesellschaft (DE) 2000-12-27 EP disclosed
US-6043387-A USEFUL AS KEY COMPONENTS IN CATALYSTS FOR ASYMMETRIC REACTIONS, PROVIDING DESIRABLY HIGH ENANTIOMERIC EXCESS MERCK & CO., INC. (US) 2000-03-28 US disclosed
EP-0942010-A1 Transition metal compounds, catalyst components and catalysts for olefin polymerization, and process for producing olefinic polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-15 EP disclosed
US-5874629-A TREATING RACEMIC PHOSPHINYL DERIVATIVE WITH DIBENZOYL-L-TARTARIC ACID A RESOLVING AGENT TO FORM ISOMERS, REDUCING TO PRODUCE CHIRAL BISPHOSPHINES; USED AS CATALYST FOR ASYMMETRIC REACTIONS MERCK & CO., INC. (US) 1999-02-23 US disclosed
US-5401857-A Process for making γ-butyrolactones ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1995-03-28 US disclosed
US-5401856-A Carbonylation of allylmethylamine ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1995-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559504-B2 Benzotriazole derivative KEAP1, NFE2L2, NCOR1 GPR3 1749/4885CA1 4424/4885CA2 3070/4885
US-10975085-B2 Process for preparing a composition comprising an enantiomeric excess of greater than or equal to 90% of the (R)-enantiomer of a compound of formula III JAK1, JAK3, JAK2 GPR3 2065/4885CA1 4747/4885CA2 4617/4885
US-20250122160-A1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF PTPN1, PTPN2, PTPN18 GPR3 4163/4885CA1 4547/4885CA2 2713/4885
US-20110288297-A1 Pyrrolo[2,3-d]Pyrimidine Derivatives; Their Intermediates and Synthesis DPYD, CPS1, TYMS GPR3 2674/4885CA1 1907/4885CA2 1119/4885
US-12129249-B2 Method for producing optically active compound DHPS, QDPR, SPR GPR3 3866/4885CA1 4105/4885CA2 1537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.