Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6633703 | 0.93 | ALDH1A1 (0.37) | KDM4ERAB9AGAAALDH1A1MAPT | |
| SCHEMBL6633780 | 0.92 | NCEH1 (0.32) | RAB9AGAANPY2R | |
| SCHEMBL6632840 | 0.91 | TDP1 (0.32) | TDP1FFAR1KDM4ERAB9AGAA | |
| SCHEMBL6635393 | 0.88 | HSD11B1 (0.32) | — | |
| SCHEMBL6632994 | 0.86 | HTR1A (0.31) | — | |
| SCHEMBL6633399 | 0.86 | KEAP1 (0.36) | GAAALDH1A1MAPT | |
| SCHEMBL6631970 | 0.85 | TDP1 (0.35) | TDP1FFAR1KDM4ERAB9AGAA | |
| SCHEMBL6634428 | 0.84 | ALDH1A1 (0.33) | KDM4ERAB9AGAAALDH1A1MAPT | |
| SCHEMBL6632020 | 0.83 | HDAC3 (0.35) | — | |
| SCHEMBL6632832 | 0.83 | NCEH1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000051-B1 | CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2004-05-19 | — | — | EP | claimed |