SCHEMBL6637473

SCHEMBL6637473

CC1=CC(C(=O)O)(c2ccccc2)C=CC1(C)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6677871 0.76 AKR1C1 (0.34) AKR1C1
SCHEMBL6681538 0.71 MEN1 (0.34) AKR1C1
SCHEMBL28890126 0.71 AKR1C1 (0.46) AKR1C1
SCHEMBL6681685 0.70 AKR1C1 (0.34) AKR1C1
SCHEMBL6679022 0.70 HCAR3 (0.33) AKR1C1
SCHEMBL6637348 0.70
SCHEMBL6680771 0.67 AKR1C1 (0.37) AKR1C1
SCHEMBL6639935 0.66 OPRM1 (0.39) AKR1C1
SCHEMBL6679652 0.66 CES2 (0.36) AKR1C1
SCHEMBL6677414 0.65 KMT2A (0.40) AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1383760-A1 BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-01-28 EP disclosed
WO-2002090347-A1 AMIDE COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-11-14 WO disclosed