Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28890126 | 0.81 | AKR1C1 (0.46) | AKR1C1CES1KMT2ATHRBLMNA | |
| SCHEMBL6677394 | 0.80 | AKR1C1 (0.37) | AKR1C1MEN1KMT2ATHRBLMNA | |
| SCHEMBL6677871 | 0.79 | AKR1C1 (0.34) | AKR1C1CES1MEN1KMT2ATHRB | |
| SCHEMBL6681538 | 0.77 | MEN1 (0.34) | AKR1C1CES1MEN1KMT2AHTT | |
| SCHEMBL6680771 | 0.77 | AKR1C1 (0.37) | AKR1C1MEN1KMT2ALMNAHTT | |
| SCHEMBL6679022 | 0.76 | HCAR3 (0.33) | AKR1C1CES1MEN1KMT2ALMNA | |
| SCHEMBL9807231 | 0.72 | HSD11B1 (0.35) | AKR1C1THRBLMNA | |
| SCHEMBL29031873 | 0.71 | CES2 (0.47) | CES1THRB | |
| SCHEMBL6637473 | 0.70 | AKR1C1 (0.30) | AKR1C1 | |
| SCHEMBL5614157 | 0.69 | HCAR3 (0.36) | AKR1C1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |