SCHEMBL6640947

SCHEMBL6640947

Cn1c(C(F)(F)F)cc(=O)n(-c2cc(Oc3nsnc3OCc3ccccc3)c(Cl)cc2F)c1=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
BCAT1 P54687 5/20 0.33
BCAT2 O15382 4/20 0.33
RHEB Q15382 1/20 0.33
PPOX P50336 3/20 0.32
PTGER1 P34995 1/20 0.32
CYP3A4 P08684 1/20 0.32
UGCG Q16739 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PKM P14618 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
LMNA P02545 1/20 0.31
GRM4 Q14833 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8926019 0.88 PPOX (0.40) ALDH1A1MEN1KMT2ABCAT1BCAT2
SCHEMBL1527259 0.87 BCAT1 (0.39) ALDH1A1MEN1KMT2ABCAT1BCAT2
SCHEMBL7237202 0.86 TRIM24 (0.39) ALDH1A1MEN1KMT2ABCAT1BCAT2
SCHEMBL6637976 0.86 PLA2G7 (0.36) ALDH1A1MEN1KMT2ABCAT1BCAT2
SCHEMBL6642464 0.85 MEN1 (0.35) ALDH1A1MEN1KMT2ABCAT1BCAT2
SCHEMBL6646370 0.85 MCL1 (0.34) ALDH1A1MEN1KMT2ABCAT1BCAT2
SCHEMBL7227825 0.85 TRIM24 (0.40) BCAT1BCAT2PPOXMAOB
SCHEMBL6639038 0.84 MEN1 (0.35) ALDH1A1MEN1KMT2ABCAT1BCAT2
SCHEMBL6638308 0.83 LMNA (0.34) PPOXLMNA
SCHEMBL6638564 0.83 PLA2G7 (0.34) ALDH1A1MEN1KMT2ABCAT1BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1122244-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2004-09-29 EP disclosed
US-6537948-B1 Have a wide range of herbicidal spectrum, and causes no phytotoxicity on crops SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-25 US disclosed
EP-1122244-A1 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-08 EP disclosed