Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648453 | 0.90 | ALDH1A1 (0.38) | CYP3A4ALDH1A1SMN1; SMN2PDE10AKDM4E | |
| SCHEMBL6645220 | 0.89 | NR3C1 (0.39) | ALDH1A1SMN1; SMN2KDM4EF2NPC1 | |
| SCHEMBL6644201 | 0.88 | F2 (0.38) | CYP3A4F2NPC1RAB9A | |
| SCHEMBL6646515 | 0.88 | KMT2A (0.38) | CYP3A4ALDH1A1SMN1; SMN2KDM4EF2 | |
| SCHEMBL6645205 | 0.87 | HCRTR1 (0.37) | CYP3A4ALDH1A1SMN1; SMN2F2CTNNB1 | |
| SCHEMBL6645763 | 0.86 | NPC1 (0.33) | ALDH1A1SMN1; SMN2KDM4EF2NPC1 | |
| SCHEMBL6646584 | 0.84 | SCN10A (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6644521 | 0.83 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL6644724 | 0.83 | KIF18A (0.37) | ALDH1A1SMN1; SMN2PDE10AKDM4ENR3C1 | |
| SCHEMBL6801997 | 0.83 | MEN1 (0.41) | ALDH1A1SMN1; SMN2F2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | CYP3A4 2434/4885ALDH1A1 2174/4885SMN1; SMN2 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.