Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645210 | 0.89 | F2 (0.37) | HCRTR1HCRTR2GRM4F2NPC1 | |
| SCHEMBL6645220 | 0.88 | NR3C1 (0.39) | ALDH1A1SMN1; SMN2TAS1R3TAS1R1NR3C1 | |
| SCHEMBL6644199 | 0.87 | CYP3A4 (0.38) | ALDH1A1SMN1; SMN2NR3C1F2CTNNB1 | |
| SCHEMBL6646515 | 0.87 | KMT2A (0.38) | ALDH1A1SMN1; SMN2NR3C1F2NPC1 | |
| SCHEMBL6646584 | 0.83 | SCN10A (0.44) | ALDH1A1SMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL6644521 | 0.82 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2GRM4NPC1RAB9A | |
| SCHEMBL6644724 | 0.82 | KIF18A (0.37) | ALDH1A1SMN1; SMN2NR3C1 | |
| SCHEMBL6794347 | 0.82 | MTTP (0.41) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6801997 | 0.81 | MEN1 (0.41) | ALDH1A1SMN1; SMN2TAS1R3TAS1R1GRM4 | |
| SCHEMBL6645324 | 0.81 | HTT (0.45) | ALDH1A1SMN1; SMN2HTTNR3C1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | HCRTR1 314/4885HCRTR2 234/4885ALDH1A1 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.