Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646487 | 0.84 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL5039765 | 0.79 | CRHR1 (0.30) | CRHR1 | |
| SCHEMBL6648719 | 0.78 | RXRA (0.35) | CRHR1 | |
| SCHEMBL6645359 | 0.76 | ACHE (0.35) | CRHR1 | |
| SCHEMBL14031211 | 0.76 | PKM (0.33) | CRHR1 | |
| SCHEMBL5039764 | 0.75 | CRHR1 (0.32) | CRHR1 | |
| SCHEMBL5043445 | 0.75 | CRHR1 (0.30) | CRHR1 | |
| SCHEMBL5046718 | 0.75 | RXRA (0.31) | — | |
| SCHEMBL5048799 | 0.75 | CRHR1 (0.35) | CRHR1 | |
| SCHEMBL14049522 | 0.74 | RXRA (0.33) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453832-A1 | RING FUSED PYRAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048160-A1 | RING FUSED PYRAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-12 | — | — | WO | disclosed |