Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645555 | 0.90 | NR3C1 (0.40) | TP53HTTRECQLNR3C1KCNA5 | |
| SCHEMBL6643633 | 0.89 | MEN1 (0.41) | TAS1R3TAS1R1RECQLNR3C1MEN1 | |
| SCHEMBL6643470 | 0.86 | RAB9A (0.41) | NR3C1MEN1POLBKMT2ARAB9A | |
| SCHEMBL6648929 | 0.83 | TAS1R3 (0.42) | TAS1R3TAS1R1TP53HTTRECQL | |
| SCHEMBL6647954 | 0.81 | ALDH1A1 (0.47) | TAS1R3TAS1R1TP53HTTRECQL | |
| SCHEMBL6645393 | 0.76 | ITGB1 (0.46) | TAS1R3TAS1R1TP53HTTRECQL | |
| SCHEMBL6644423 | 0.76 | NPC1 (0.39) | TP53HTTMEN1KMT2ARAB9A | |
| SCHEMBL6646113 | 0.74 | ALDH1A1 (0.40) | TP53HTTNR3C1MEN1POLB | |
| SCHEMBL6643607 | 0.73 | FLT1 (0.43) | TP53HTTNR3C1RAB9AJAK2 | |
| SCHEMBL6647070 | 0.73 | ALDH1A1 (0.41) | NR3C1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | TAS1R3 3106/4885TAS1R1 2303/4885TP53 4513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.