Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645976 | 0.83 | TRPV4 (0.32) | TP53F2TRPV4 | |
| SCHEMBL6647215 | 0.80 | SCD (0.40) | MAPT | |
| SCHEMBL6643944 | 0.78 | DGAT1 (0.32) | TRPV4SLC6A4 | |
| SCHEMBL6645363 | 0.76 | IRAK4 (0.34) | F2TRPV4 | |
| SCHEMBL6648470 | 0.76 | F2 (0.36) | TP53F2SLC6A4 | |
| SCHEMBL6647209 | 0.74 | THRB (0.37) | TP53MAPTF2 | |
| SCHEMBL6645762 | 0.74 | ADORA3 (0.38) | TP53MAPT | |
| SCHEMBL6645002 | 0.73 | F2 (0.37) | F2 | |
| SCHEMBL6645757 | 0.69 | THRB (0.35) | TP53F2 | |
| SCHEMBL6500413 | 0.67 | TP53 (0.35) | TP53F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | TP53 4513/4885MAPT 4101/4885F2 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.