Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368137 | 0.97 | LMNA (0.39) | LMNAF2SIGMAR1HTR2C | |
| SCHEMBL6676171 | 0.87 | F2 (0.32) | F2 | |
| SCHEMBL6648539 | 0.87 | SIGMAR1 (0.37) | F2SIGMAR1HTR2C | |
| SCHEMBL9868832 | 0.81 | SIGMAR1 (0.39) | F2SIGMAR1HTR2C | |
| SCHEMBL6649065 | 0.81 | IDO1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6586236 | 0.79 | HTR2C (0.41) | F2SIGMAR1HTR2C | |
| SCHEMBL7014444 | 0.77 | PDCD1 (0.42) | LMNA | |
| SCHEMBL5401265 | 0.76 | SIGMAR1 (0.34) | F2SIGMAR1HTR2C | |
| SCHEMBL6648602 | 0.75 | SIGMAR1 (0.36) | F2SIGMAR1HTR2C | |
| SCHEMBL6648243 | 0.75 | SIGMAR1 (0.36) | F2SIGMAR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469854-A1 | CONDENSED HETEROCYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-1355888-A1 | QUINAZOLINONE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2003063874-A1 | CONDENSED HETEROCYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-08-07 | — | — | WO | disclosed |
| WO-2002048117-A1 | QUINAZOLINONE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-20 | — | — | WO | disclosed |