Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868832 | 0.79 | SIGMAR1 (0.39) | SIGMAR1F2HTR2C | |
| SCHEMBL6648243 | 0.78 | SIGMAR1 (0.36) | SIGMAR1F2HTR2C | |
| SCHEMBL10849078 | 0.77 | ALDH1A1 (0.39) | HTR2CKMT2A | |
| SCHEMBL6648237 | 0.76 | LMNA (0.41) | SIGMAR1F2HTR2C | |
| Hydrochloric Acid SCHEMBL6586236 | 0.76 | HTR2C (0.41) | SIGMAR1F2HTR2C | |
| SCHEMBL10849506 | 0.75 | MMP2 (0.37) | KMT2A | |
| SCHEMBL6648602 | 0.75 | SIGMAR1 (0.36) | SIGMAR1F2HTR2C | |
| SCHEMBL9726241 | 0.74 | ESR1 (0.42) | KMT2A | |
| SCHEMBL6368137 | 0.74 | LMNA (0.39) | SIGMAR1F2HTR2C | |
| SCHEMBL10851305 | 0.74 | ALDH1A1 (0.38) | HTR2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007516939-A | — | — | 2007-06-28 | — | — | JP | claimed |
| EP-1644325-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | Neurochem (International) Limited (CH) | 2006-04-12 | — | — | EP | claimed |
| WO-2004113275-A2 | METHODS AND COMPOSITIONS FOR TREATING AMYLOID-RELATED DISEASES | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-12-29 | — | — | WO | claimed |
| EP-1237547-A2 | COMPOUNDS FOR INHIBITING DISEASES AND PREPARING CELLS FOR TRANSPLANTATION | ISIS INNOVATION LIMITED (GB) | 2002-09-11 | — | — | EP | claimed |
| WO-2001003680-A2 | COMPOUNDS FOR INHIBITING DISEASES AND PREPARING CELLS FOR TRANSPLANTATION | ISIS INNOVATION LIMITED (GB) | 2001-01-18 | — | — | WO | claimed |
| EP-1646659-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | Neurochem (International) Limited (CH) | 2006-04-19 | — | — | EP | disclosed |
| WO-2004113391-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-12-29 | — | — | WO | disclosed |
| EP-1237547-A2 | COMPOUNDS FOR INHIBITING DISEASES AND PREPARING CELLS FOR TRANSPLANTATION | ISIS INNOVATION LIMITED (GB) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001003680-A2 | COMPOUNDS FOR INHIBITING DISEASES AND PREPARING CELLS FOR TRANSPLANTATION | ISIS INNOVATION LIMITED (GB) | 2001-01-18 | — | — | WO | disclosed |