Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868832 | 0.81 | SIGMAR1 (0.39) | SIGMAR1HTR2CF2 | |
| SCHEMBL5401265 | 0.78 | SIGMAR1 (0.34) | SIGMAR1HTR2CF2 | |
| Hydrochloric Acid SCHEMBL6586236 | 0.78 | HTR2C (0.41) | SIGMAR1HTR2CF2 | |
| SCHEMBL6648602 | 0.77 | SIGMAR1 (0.36) | SIGMAR1HTR2CF2 | |
| SCHEMBL6648237 | 0.75 | LMNA (0.41) | SIGMAR1HTR2CF2 | |
| SCHEMBL6368536 | 0.75 | SIGMAR1 (0.34) | SIGMAR1HTR2CF2 | |
| SCHEMBL5265951 | 0.74 | POLB (0.44) | SIGMAR1HTR2C | |
| SCHEMBL9582090 | 0.73 | MCL1 (0.39) | HTR2C | |
| SCHEMBL6368137 | 0.73 | LMNA (0.39) | SIGMAR1HTR2CF2 | |
| SCHEMBL9726241 | 0.71 | ESR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1469854-A1 | CONDENSED HETEROCYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063874-A1 | CONDENSED HETEROCYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-08-07 | — | — | WO | disclosed |