Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6586236 | 0.91 | HTR2C (0.41) | SIGMAR1HTR2CHRH1F2 | |
| Hydrochloric Acid SCHEMBL11182448 | 0.82 | TAAR1 (0.38) | HTR2CHTR2A | |
| SCHEMBL6648237 | 0.81 | LMNA (0.41) | SIGMAR1HTR2CF2 | |
| SCHEMBL6648243 | 0.81 | SIGMAR1 (0.36) | SIGMAR1HTR2CF2 | |
| SCHEMBL6648602 | 0.81 | SIGMAR1 (0.36) | SIGMAR1HTR2CF2 | |
| SCHEMBL6368137 | 0.79 | LMNA (0.39) | SIGMAR1HTR2CF2 | |
| SCHEMBL6368536 | 0.79 | SIGMAR1 (0.34) | SIGMAR1HTR2CF2 | |
| SCHEMBL6645604 | 0.78 | PNMT (0.41) | — | |
| SCHEMBL5265951 | 0.78 | POLB (0.44) | SIGMAR1HTR2C | |
| SCHEMBL10481310 | 0.75 | NOS1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999355-A | Antiserotonine agents | RHONE-POULENC (FR) | 1991-03-12 | — | — | US | disclosed |