Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691418 | 0.81 | MTTP (0.59) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8408661 | 0.80 | MTTP (0.59) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3887925 | 0.80 | MTTP (0.59) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8410108 | 0.79 | MTTP (0.58) | MAPTKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6649251 | 0.79 | TMPRSS2 (0.56) | MEN1KMT2ATP53MAPTGAA | |
| SCHEMBL6647429 | 0.78 | NOD1 (0.45) | MEN1KMT2AABCB1ABCG2SMN1; SMN2 | |
| SCHEMBL6648762 | 0.77 | SIGMAR1 (0.52) | POLBHSD17B10ABCB1ABCG2SIGMAR1 | |
| SCHEMBL28715681 | 0.77 | NPC1 (0.66) | MEN1KMT2ATP53MAPTHSD17B10 | |
| SCHEMBL13135946 | 0.76 | ALOX15 (0.62) | MEN1KMT2ATP53ALOX15MAPT | |
| SCHEMBL6492509 | 0.75 | PLAU (0.47) | MEN1KMT2ATP53ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040133008-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-08 | — | — | US | disclosed |
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040133008-A1 | Amide compounds | APOB, APOL1, LDLR | MEN1 3820/4885KMT2A 916/4885TP53 4513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.