Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650451 | 0.87 | LMNA (0.39) | LMNACHRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6654163 | 0.80 | HRH3 (0.35) | LMNACHRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6648700 | 0.77 | HRH3 (0.35) | CHRM2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL6672328 | 0.76 | TRPM5 (0.32) | LMNACHRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6650409 | 0.75 | L3MBTL1 (0.40) | CYP2D6TSHROPRK1MEN1KMT2A | |
| SCHEMBL6649435 | 0.75 | OPRK1 (0.37) | LMNACHRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21721828 | 0.73 | HTR1D (0.43) | TSHROPRK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6649371 | 0.73 | HTR1A (0.32) | LMNAHTR2CCHRNB2CHRNA4HTR1A | |
| SCHEMBL6650639 | 0.72 | POLB (0.39) | LMNACHRM2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6650689 | 0.70 | L3MBTL1 (0.40) | LMNACYP2D6CYP2C19CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |