Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474075 | 0.74 | GAA (0.52) | GAAALDH1A1HPGD | |
| SCHEMBL6653068 | 0.70 | ALDH1A1 (0.32) | GAAALDH1A1HPGD | |
| SCHEMBL6652064 | 0.69 | GAA (0.56) | GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL6652810 | 0.69 | ALDH1A1 (0.31) | GAAALDH1A1HPGD | |
| SCHEMBL669124 | 0.62 | ADRA2A (0.34) | GAA | |
| SCHEMBL28521977 | 0.60 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL28770641 | 0.60 | ALDH1A1 (0.33) | GAAALDH1A1LMNAHPGD | |
| SCHEMBL8964833 | 0.59 | POLB (0.33) | ALDH1A1HPGD | |
| SCHEMBL1158351 | 0.58 | ALOX5 (0.42) | GAAALDH1A1HPGD | |
| SCHEMBL12917966 | 0.55 | PRSS1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054886-B1 | HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS, IN PARTICULAR AS UROKINASE INHIBITORS | DIMENSIONAL PHARM INC (US) | 2002-09-04 | — | — | EP | claimed |