Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 4/20 | 0.51 |
| ▸ | ABCC8 | Q09428 | 4/20 | 0.51 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.51 |
| ▸ | KCNJ8 | Q15842 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3953118 | 0.87 | CYP2C19 (0.52) | LMNAMEN1KMT2ACNR2AR | |
| SCHEMBL2782039 | 0.77 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8MEN1 | |
| SCHEMBL28077906 | 0.72 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8MEN1 | |
| SCHEMBL4846044 | 0.70 | CYP2C19 (0.51) | LMNAMEN1KMT2ASMN1; SMN2CNR2 | |
| SCHEMBL8407102 | 0.69 | LMNA (0.66) | LMNAMEN1KMT2ACNR2AR | |
| SCHEMBL24769840 | 0.68 | DHODH (0.50) | LMNAMEN1KMT2AMAPTHTT | |
| SCHEMBL28777075 | 0.68 | LMNA (0.54) | LMNAMEN1KMT2ACNR2CYP2C19 | |
| SCHEMBL8866328 | 0.68 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11KCNJ8MEN1 | |
| SCHEMBL9819042 | 0.68 | MAOB (0.47) | LMNAMEN1KMT2ASMN1; SMN2RORC | |
| SCHEMBL9818907 | 0.68 | MAOB (0.47) | LMNAMEN1KMT2ASMN1; SMN2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439823-A1 | PHARMACEUTICAL FORMULATION COMPRISING (R)-BICALUTAMIDE | AstraZeneca UK Limited (GB) | 2004-07-28 | — | — | EP | claimed |
| WO-2003032950-A1 | PHARMACEUTICAL FORMULATION COMPRISING (R) -BICALUTAMIDE | ASTRAZENECA AB (SE) | 2003-04-24 | — | — | WO | claimed |