Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL2802759 | 0.98 | FABP3 (0.50) | FABP3EPHX1ALDH1A1TSHRCA1 | |
| SCHEMBL29543143 | 0.96 | FABP3 (0.50) | FABP3EPHX1ALDH1A1TSHRCA1 | |
| SCHEMBL1115447 | 0.96 | CA1 (0.52) | FABP3EPHX1ALDH1A1TSHRCA1 | |
| SCHEMBL22534532 | 0.96 | CA1 (0.52) | FABP3EPHX1ALDH1A1TSHRCA1 | |
| SCHEMBL1490963 | 0.96 | CA1 (0.52) | FABP3EPHX1ALDH1A1TSHRCA1 | |
| SCHEMBL6660469 | 0.96 | CA1 (0.52) | FABP3EPHX1ALDH1A1TSHRCA1 | |
| SCHEMBL11627739 | 0.96 | FABP3 (0.50) | FABP3EPHX1ALDH1A1TSHRCA1 | |
| SCHEMBL10484717 | 0.96 | FABP3 (0.50) | FABP3EPHX1ALDH1A1TSHRCA1 | |
| SCHEMBL321998 | 0.94 | CA1 (0.54) | FABP3EPHX1ALDH1A1TSHRCA1 | |
| Acetic Acid SCHEMBL8858976 | 0.92 | FABP3 (0.47) | FABP3EPHX1ALDH1A1TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268436-B1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-08-18 | — | — | EP | claimed |
| EP-1443886-A1 | SHAMPOO COMPOSITIONS WITH ANIONIC SURFACTANTS, AMPHOTERIC SURFACTANTS AND CATIONIC POLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 2004-08-11 | — | — | EP | claimed |
| US-20030108507-A1 | Shampoo compositions with anionic surfactants, amphoteric surfactants and cationic polymers | THE PROCTER & GAMBLE COMPANY | 2003-06-12 | — | — | US | claimed |
| WO-2003032935-A1 | SHAMPOO COMPOSITIONS WITH ANIONIC SURFACTANTS, AMPHOTERIC SURFACTANTS AND CATIONIC POLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 2003-04-24 | — | — | WO | claimed |
| US-20220079898-A1 | SURFACTANTS FOR THE TREATMENT OF CONDITIONS THROUGH TARGETED NECROSIS | IMUNEKS FARMA ILAC SAN. VE TIC. A.S. (TR) | 2022-03-17 | — | — | US | disclosed |
| US-20200188328-A1 | SURFACTANTS FOR THE TREATMENT OF CONDITIONS THROUGH TARGETED NECROSIS | IMUNEKS FARMA ILAC SAN. VE TIC. A.S. (TR) | 2020-06-18 | — | — | US | disclosed |
| EP-1443886-A1 | SHAMPOO COMPOSITIONS WITH ANIONIC SURFACTANTS, AMPHOTERIC SURFACTANTS AND CATIONIC POLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 2004-08-11 | — | — | EP | disclosed |
| US-20030108507-A1 | Shampoo compositions with anionic surfactants, amphoteric surfactants and cationic polymers | THE PROCTER & GAMBLE COMPANY | 2003-06-12 | — | — | US | disclosed |
| WO-2003032935-A1 | SHAMPOO COMPOSITIONS WITH ANIONIC SURFACTANTS, AMPHOTERIC SURFACTANTS AND CATIONIC POLYMERS | THE PROCTER & GAMBLE COMPANY (US) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220079898-A1 | SURFACTANTS FOR THE TREATMENT OF CONDITIONS THROUGH TARGETED NECROSIS | KRT18, ANXA5, ANXA11 | FABP3 3396/4885EPHX1 2014/4885ALDH1A1 3755/4885 |
| US-20030108507-A1 | Shampoo compositions with anionic surfactants, amphoteric surfactants and cationic polymers | SCO2, HAO2, PAOX | FABP3 1838/4885EPHX1 4032/4885ALDH1A1 3605/4885 |
| US-20200188328-A1 | SURFACTANTS FOR THE TREATMENT OF CONDITIONS THROUGH TARGETED NECROSIS | KRT18, ANXA5, ANXA11 | FABP3 3396/4885EPHX1 2014/4885ALDH1A1 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.