Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | FABP3 | P05413 | 5/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490963 | 0.98 | CA1 (0.52) | CA1ALDH1A1TSHRFABP3EPHX1 | |
| SCHEMBL22534532 | 0.98 | CA1 (0.52) | CA1ALDH1A1TSHRFABP3EPHX1 | |
| SCHEMBL6660469 | 0.98 | CA1 (0.52) | CA1ALDH1A1TSHRFABP3EPHX1 | |
| SCHEMBL1115447 | 0.98 | CA1 (0.52) | CA1ALDH1A1TSHRFABP3EPHX1 | |
| Potassium Ion SCHEMBL2802759 | 0.96 | FABP3 (0.50) | CA1ALDH1A1TSHRFABP3EPHX1 | |
| Dodicin SCHEMBL29987916 | 0.94 | ALDH1A1 (0.50) | CA1ALDH1A1TSHRFABP3EPHX1 | |
| SCHEMBL610050 | 0.94 | ALDH1A1 (0.50) | CA1ALDH1A1TSHRFABP3EPHX1 | |
| SCHEMBL11627739 | 0.94 | FABP3 (0.50) | CA1ALDH1A1TSHRFABP3EPHX1 | |
| Potassium Ion SCHEMBL6660182 | 0.94 | FABP3 (0.53) | CA1ALDH1A1TSHRFABP3EPHX1 | |
| SCHEMBL10484717 | 0.94 | FABP3 (0.50) | CA1ALDH1A1TSHRFABP3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612092-B | Liquid personal cleansing compositions | 联合利华知识产权控股有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-110612092-A | Liquid personal cleansing compositions | 荷兰联合利华有限公司 | 2019-12-24 | — | — | CN | disclosed |
| EP-2870136-B1 | PROCESS FOR PREPARING N-ACYL AMINO ACID SALTS | STEPAN CO (US) | 2018-10-24 | — | — | EP | disclosed |
| US-20160074310-A1 | Composition Containing Oil Bodies, Fatty Acids, Amino Acid Surfactants And N-Methyl-N-Acylglucamines | CLARIANT INTERNATIONAL LTD. (CH) | 2016-03-17 | — | — | US | disclosed |
| US-9242124-B2 | Low-temperature phase-stable acyl glycinate compositions | RHODIA OPERATIONS (FR) | 2016-01-26 | — | — | US | disclosed |
| US-9156777-B2 | Process for preparing N-acyl amino acid salts | STEPAN COMPANY (US) | 2015-10-13 | — | — | US | disclosed |
| EP-2870136-A1 | PROCESS FOR PREPARING N-ACYL AMINO ACID SALTS | Stepan Company (US) | 2015-05-13 | — | — | EP | disclosed |
| US-20150126776-A1 | PROCESS FOR PREPARING N-ACYL AMINO ACID SALTS | STEPAN COMPANY | 2015-05-07 | — | — | US | disclosed |
| US-20150011456-A1 | LOW-TEMPERATURE PHASE-STABLE ACYL GLYCINATE COMPOSITIONS | RHODIA OPERATIONS (FR) | 2015-01-08 | — | — | US | disclosed |
| WO-2014008103-A1 | PROCESS FOR PREPARING N-ACYL AMINO ACID SALTS | STEPAN COMPANY (US) | 2014-01-09 | — | — | WO | disclosed |
| US-8350080-B2 | Method for the production of acyl glycinates by means of direct oxidation | CLARIANT FINANCE (BVI) LIMITED (BV) | 2013-01-08 | — | — | US | disclosed |
| US-8093414-B2 | Process for preparing acylglycinates by means of direct oxidation | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-01-10 | — | — | US | disclosed |
| US-20100305358-A1 | Method For The Production Of Acyl Glycinates By Means Of Direct Oxidation | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-12-02 | — | — | US | disclosed |
| US-20100286418-A1 | Process For Preparing Acylglycinates By Means Of Direct Oxidation | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-11-11 | — | — | US | disclosed |
| JP-2009007281-A | SKIN DETERGENT COMPOSITION AND SKIN DETERGENT | P & P F:KK | 2009-01-15 | — | — | JP | disclosed |
| EP-1000606-B1 | Weak acid skin cleanser containing an alkali salt of N-acyl-amino acid | AJINOMOTO KK (JP) | 2007-02-14 | — | — | EP | disclosed |
| US-6582687-B1 | Skin cleanser containing an alkali salt of N- acylamino acid and maltitolhydroxy aliphatic ether, or a hydroxy ether carboxylic acid-based anionic surfactant, or polyethylene powder, as well as water and an organic acid. Also, | SHISEIDO COMPANY, LTD. (JP) | 2003-06-24 | — | — | US | disclosed |
| EP-1000606-A2 | Weak acid skin cleanser containing an alkali salt of N-acyl-amino acid | SHISEIDO COMPANY LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286418-A1 | Process For Preparing Acylglycinates By Means Of Direct Oxidation | FADS1, UGCG, AGPAT2 | CA1 440/4885ALDH1A1 463/4885TSHR 3205/4885 |
| US-20150011456-A1 | LOW-TEMPERATURE PHASE-STABLE ACYL GLYCINATE COMPOSITIONS | ALG1, FUT5, FUT6 | CA1 270/4885ALDH1A1 3618/4885TSHR 4049/4885 |
| US-20160074310-A1 | Composition Containing Oil Bodies, Fatty Acids, Amino Acid Surfactants And N-Methyl-N-Acylglucamines | DGAT2, SGMS2, FABP4 | CA1 3826/4885ALDH1A1 2836/4885TSHR 4201/4885 |
| US-20100305358-A1 | Method For The Production Of Acyl Glycinates By Means Of Direct Oxidation | ACOX1, ACOX3, ACADM | CA1 66/4885ALDH1A1 146/4885TSHR 2123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.