Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658785 | 0.88 | CHRNB4 (0.44) | LTA4HPTGS2CHRNB4CHRNA3HRH3 | |
| SCHEMBL6661071 | 0.84 | HRH3 (0.43) | CHRNB4CHRNA3MAPTTEAD1TEAD3 | |
| SCHEMBL6658483 | 0.84 | MAPT (0.45) | LTA4HPTGS2CHRNB4CHRNA3MAPT | |
| SCHEMBL6660658 | 0.84 | CHRNB4 (0.43) | LTA4HPTGS2CHRNB4CHRNA3MAPT | |
| SCHEMBL6657367 | 0.83 | HTR6 (0.42) | LTA4HPTGS2ACHESIGMAR1HRH3 | |
| SCHEMBL6663521 | 0.83 | ACHE (0.40) | DRD2DRD4DRD3MAPTACHE | |
| SCHEMBL6657190 | 0.81 | KCNH2 (0.42) | LTA4HPTGS2CHRNB4CHRNA3MAPT | |
| SCHEMBL6657776 | 0.81 | MAOB (0.48) | CHRNB4CHRNA3ALDH1A1MEN1KMT2A | |
| SCHEMBL6656594 | 0.80 | ACHE (0.41) | DRD2MAPTACHEKDM4EALDH1A1 | |
| SCHEMBL6656357 | 0.80 | ALDH1A1 (0.44) | CHRNB4CHRNA3MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |