Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658483 | 0.91 | MAPT (0.45) | CHRNB4CHRNA3MAPTLMNAALDH1A1 | |
| SCHEMBL6658785 | 0.88 | CHRNB4 (0.44) | CHRNB4CHRNA3HTR1AHTR7CHRNB2 | |
| SCHEMBL6657776 | 0.87 | MAOB (0.48) | CHRNB4CHRNA3ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL6656357 | 0.86 | ALDH1A1 (0.44) | CHRNB4CHRNA3MAPTKDM4EPOLB | |
| SCHEMBL6657190 | 0.85 | KCNH2 (0.42) | CHRNB4CHRNA3MAPTCHRNB2CHRNA4 | |
| SCHEMBL6661071 | 0.85 | HRH3 (0.43) | CHRNB4CHRNA3MAPTPOLBSMN1; SMN2 | |
| SCHEMBL6661589 | 0.84 | LTA4H (0.41) | CHRNB4CHRNA3MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL6657970 | 0.84 | ACHE (0.39) | CHRNB4CHRNA3MAPTCYP1A2CYP3A4 | |
| SCHEMBL6657367 | 0.84 | HTR6 (0.42) | KDM4ESMN1; SMN2ALDH1A1LTA4HPTGS2 | |
| SCHEMBL6659951 | 0.82 | MAPT (0.40) | CHRNB4CHRNA3MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |