Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656357 | 0.91 | ALDH1A1 (0.44) | MAOBALDH1A1CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL6661071 | 0.90 | HRH3 (0.43) | MAOBALDH1A1CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL6658483 | 0.87 | MAPT (0.45) | ALDH1A1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL6660658 | 0.87 | CHRNB4 (0.43) | ALDH1A1CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL6658785 | 0.85 | CHRNB4 (0.44) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL6657190 | 0.84 | KCNH2 (0.42) | CHRNB4CHRNA3CHRNB2CHRNA4MEN1 | |
| SCHEMBL6658813 | 0.82 | MEN1 (0.44) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6661589 | 0.81 | LTA4H (0.41) | ALDH1A1CHRNB4CHRNA3MEN1KMT2A | |
| SCHEMBL6657970 | 0.81 | ACHE (0.39) | ALDH1A1CHRNB4CHRNA3MEN1KMT2A | |
| SCHEMBL6657367 | 0.81 | HTR6 (0.42) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |